Updates have been made to the Sentinel Field Guide, which incorporate the most recent World Health Organization recommendations on the management of TB in children and adolescents. You can access the fifth edition of the Sentinel Field Guide here or on our Resources page.
The Paediatric Drug-Resistant TB Donation Initiative is led and funded by the Stop TB Partnership’s Global Drug Facility in partnership and with financial support from USAID.
Management of Multidrug-Resistant Tuberculosis in Children: A Field Guide / (Russian)
Standard Operating Procedures for Administration of Dispersible Formulations of Second-Line Drugs For Clinical/Nursing Personnel / (Russian) / (French)
Drug Sheets for Dispersible Formulations / (Russian) / (French)
DR-TB & Me: Caring for a child with drug resistant TB / (Russian)
Standard Operating Procedures for Storage and Administration of Dispersible Formulations of Second-Line Drugs for Pharmacy Personnel / (Russian) / (French)
Pediatric Formulations of Second-Line Drugs for the Treatment of Drug-Resistant Tuberculosis / (Russian)
Summary Points on Pediatric Formulations of Second-Line Drugs for Tuberculosis / (Russian)
The Sentinel Project resource, “How to Care for People Exposed to Drug-Resistant Tuberculosis: A Practical Guide” is now available.
This Guide builds on World Health Organization (WHO) recommendations for the management of individuals who have been exposed to TB and DR-TB, but focuses more on the practical implementation of interventions that should take place in the post-exposure setting. While the WHO policies stress that investigating household contacts of TB patients must be done on an “urgent” basis for all contacts of a patient with DR-TB, there is limited information available on what these evaluations and interventions should include. Furthermore, many of the recommendations and tools that do exist only focus on medical issues, omitting other pressing psychosocial needs that must be routinely assessed as well. DR-TB affects not only individuals but their households as well. Even when only one person has become sick, the whole household requires some intervention to reduce discrimination, improve patient support, and avoid unnecessary morbidity and mortality. This Guide aims to provide a way of thinking about the challenges around those exposed to DR-TB. It also aims to provide guidance on DR-TB prevention and management strategies needed to address the enormous health threat presented by DR-TB, as well as the tools necessary to carry them out.
This Guide is available in English and Spanish.
For additional translations of the Field Guide, please send a note to Sentinel_Project@hms.harvard.edu.
The Sentinel Project resource “Management of Multidrug-Resistant Tuberculosis in Children: A Field Guide, Third Edition” is now available.
This field guide is meant to serve as a tool for practitioners working with children at risk of infection or becoming sick with MDR-TB. This guide was developed by a team of experts who jointly have treated hundreds of children with MDR-TB over the last two decades in every region of the world. We hope it will be used in the field to rapidly increase the number of children receiving effective care for MDR-TB.
The guide focuses on issues relevant in clinical and programmatic practices and does not offer extensive background materials on management of MDR-TB, which can be found here. Case examples are included throughout the guide to demonstrate how the recommendations put forth in the field guide can be translated into practice. The third edition features updated information and incorporates two new anti-tubercular agents, bedaquiline and delamanid.
The third edition of the Field Guide is available in English and Spanish.
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For additional translations of the Field Guide, please send a note to Sentinel_Project@hms.harvard.edu.
The Harvard Medical School Center for Global Health Delivery–Dubai celebrated its inaugural symposium on Sunday, October 25, 2015 at the Mohammed Bin Rashid Academic Medical Center in Dubai Healthcare City. At the launch, the Center distributed a policy brief, “Post-Exposure Management of Multidrug-Resistant Tuberculosis Contacts: Evidence-Based Recommendations,” which was written by Sentinel Project members.
The principles and recommendations outlined in this policy brief were developed by a global panel of 51 tuberculosis practitioners from 33 cities in 19 countries who gathered at the Harvard Medical School Center for Global Health Delivery–Dubai on April 12 and 13, 2015. This global consultation provided a forum for TB practitioners to synthesize evidence and produce practical guidance for the management of children and adults who are household contacts of patients with DR-TB. Following the meetings and a review of published and unpublished evidence, the panel arrived at a set of seven principles summarized in this policy brief, along with the process employed to produce them.