The Sentinel Project resource “Get the Facts about Drug-Resistant Tuberculosis: A Resource for Families” is now available on our site. It serves as a quick guide on DR-TB and how best to manage and treat it.
Get the Facts about Drug-Resistant Tuberculosis: A Resource for Families
Мы, как опытные SEO-специалисты и копирайтеры, знаем, что одним из ключевых факторов для успешного ранжирования в поисковой системе Google является качество контента. Именно поэтому мы хотим представить вам нашу статью о том, почему игра “Плинко” может быть отличным выбором для будущих мам. Наша цель – помочь вам понять, как качественный контент может привести вас к вершинам поисковых результатов.
Почему стоит играть в Плинко во время беременности?
Увлекательный и расслабляющий опыт
Игра “Плинко” известна своей увлекательностью и способностью расслабить. В это период жизни, когда женщина переживает много стрессов и изменений, игра в Плинко может стать отличным способом расслабиться и отвлечься от повседневных забот.
Семейное развлечение
Игра “Плинко” – это отличный способ провести время в кругу семьи. Это соберет всех ваших близких вокруг телевизора, и вы сможете насладиться игрой вместе. Это также отличный момент для создания воспоминаний, которые будут дороги вам и вашей семье на протяжении многих лет.
Улучшение настроения
Беременность часто сопровождается переменами в настроении из-за гормональных изменений. Игра “Плинко” способствует выработке эндорфинов, которые могут улучшить ваше настроение и создать ощущение радости и удовольствия.
Ответ на вопрос: “Плинко – хорошая игра, когда вы беременны?”
Итак, ответ на данный вопрос очевиден: да, Плинко – отличная игра, когда вы беременны. Она способствует расслаблению, улучшает настроение и создает возможность провести время с семьей. Этот игровой опыт может стать приятным и полезным аспектом вашей беременности.
Заключение
В нашей статье мы представили аргументы в пользу игры “Плинко” во время беременности. Мы убеждены, что этот контент предоставляет важную информацию для будущих мам и поможет им сделать правильный выбор в пользу увлекательного и положительного времяпрепровождения в ожидании малыша.
The Sentinel Project resource “Management of Multidrug-Resistant Tuberculosis in children: A Field Guide, Fourth Edition” is now available in English and Russian.
There have been some important changes to the delamanid compassionate use protocol. Delamanid is available for compassionate use and can be obtained from the company at no charge on a patient-by-patient basis.
The company has made some changes to their access and eligibility criteria and these are summarized below. Perhaps most exciting is that the pediatric formulation of delamanid (a 25mg dispersible tablet) will also be available via compassionate use. This formulation is not yet on the market but is an important tool for younger children with RR-TB. We are thrilled the company has now made this formulation available for the children who need it.
Male and female patients ≥ 3 years of age are eligible for CU DLM enrolment
Prior delamanid use is no longer an exclusion criterion
DLM treatment duration
The current protocol 242-302-00014 allows treatment extension of CU DLM on a case by case basis. Re-application for a treatment extension with delamanid can be made in exceptional cases, in order to minimize the probability of a resistance development to anti-TB treatment and/or enhance the likelihood of a favourable treatment outcome in difficult to treat cases.
Pediatric formulation
IMP of the pediatric formulation (dispersible tablets of 25 mg) is undergoing final packaging and testing and shall become available for patients enrolled in the updated CU protocol 242-302-00014 shortly.
PV reporting timelines
The updated CU protocol 242-302-00014 requires reporting of all safety information within 24 hours (not just for SAE as in the previous CU protocol 242-12-401 but all AEs + safety information)
The Paediatric Drug-Resistant TB Donation Initiative isled and funded by the Stop TB Partnership’s Global Drug Facility in partnership and with financial support from USAID.
In June 2018, the South African National Department of Health announced that bedaquiline will now be used to replace the injectable agent in routine treatment of rifampin-resistant and multidrug resistant tuberculosis (RR/MDR-TB) in patients over 12 years of age. We congratulate the leadership of the South African National TB program for taking this important step.
We note with some concern that children under the age of 12 years may be precluded from accessing the benefits of an all-oral RR/MDR-TB regimen. As such, we call for policies to support all-oral regimens for patients under 12 years of age in South Africa and globally. In partnership with the Desmond Tutu Tuberculosis Centre (DTTC) and Treatment Action Group (TAG), Sentinel Project has developed the following recommendations for injectable-free regimens for children under the age of 12 years.
Please download these recommendations here: Recommendations for Injectible-Free Regimens in Children with Rifampacin Resistant TB.
The Sentinel Project has assembled a list of publications highlighting DR-TB in children and adolescents published in 2017. This list can be found here.
The Sentinel Project resource, “How to Care for People Exposed to Drug-Resistant Tuberculosis: A Practical Guide” is now available.
This Guide builds on World Health Organization (WHO) recommendations for the management of individuals who have been exposed to TB and DR-TB, but focuses more on the practical implementation of interventions that should take place in the post-exposure setting. While the WHO policies stress that investigating household contacts of TB patients must be done on an “urgent” basis for all contacts of a patient with DR-TB, there is limited information available on what these evaluations and interventions should include. Furthermore, many of the recommendations and tools that do exist only focus on medical issues, omitting other pressing psychosocial needs that must be routinely assessed as well. DR-TB affects not only individuals but their households as well. Even when only one person has become sick, the whole household requires some intervention to reduce discrimination, improve patient support, and avoid unnecessary morbidity and mortality. This Guide aims to provide a way of thinking about the challenges around those exposed to DR-TB. It also aims to provide guidance on DR-TB prevention and management strategies needed to address the enormous health threat presented by DR-TB, as well as the tools necessary to carry them out.
On November 21, 2017, the Sentinel Project co-sponsored a webinar with DR-TB STAT, entitled “MDR-TB Treatment with Bedaquiline in Children and Adolescents: Global Recommendations and Program Experience in Belarus.” Dr. Alena Skrahina, MD, PhD, DSc, presented interim results of bedaquiline use in the treatment of children and adolescents with multi-drug resistant tuberculosis in Belarus. Dr. Skrahina discussed the acceptability of bedaquiline-containing regimens, culture conversion results, and the occurrence of adverse events. Dr. Skrahina was joined by Dr. Jennifer Furin as commentator and moderator.